Biology
As part of the patient treatment procedure, mandatory samples (blood and urine) and optional samples (cerebrospinal fluid and stools) are taken and sent to the participating Biological Resource Centers (BRCs). The patients correspond to sub-populations of specific interest to research, called nested cohorts.
The samples are then taken and cryopreserved by technicians in the participant BRCs according to standardized procedures (sample form). Furthermore, the collaboration project between Généthon and REFGENSEP BRC also enables the extraction and storage of DNA. The collection of biological samples from multiple centers is thus compiled and the associated data are centralized in a TK® database.
Documents (in French)
- Sample management manual [v9.0 - Application date 18/09/2023]
- Sample form [v7.0 - Application date 20/06/2024]
- Saliva sample questionnaire [v2.0 - Application date 06/10/2022]
- Sample treatment protocol [v9.0 - Application date 18/09/2023]
- EDMUS - Samples panel and biological cohorts [Guide FMO v4.0, page 47 - Application date 26/09/2022]
- Inclusion criteria of biological cohorts: practical guide (in French) [v10.0 - Application date 20/06/2024]
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